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点击科学

陶 陶 编译

2018-02/总第263期

阅读数3

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2018-01-05

封面插图上展示的是将肠道微生物菌群汇聚成癌症感知带的形状。具有大量不同肠道细菌的癌症患者在接受检查点抑制剂免疫疗法后,会有更高的生存几率,而肠道菌群减少的患者对这种治疗反应很差。因此,调节微生物群组也许能够为改善癌症患者的治疗效果提供希望。

Illustration of gut microbial species assembling into the shape of a cancer awareness ribbon. Cancer patients with an abundance of different gut bacteria have better survival outcomes after checkpoint inhibitor immunotherapy, whereas patients with depleted gut flora respond poorly to this treatment. Thus, modulating the microbiome may provide hope for improved cancer patient responses.


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2018-01-12

封面插图重构呈现了玛丽·雪莱在1818年的小说中第一次出现的怪物。2个世纪后,虚构的弗兰肯斯坦博士利用捡来的身体残肢制造了一种生物,并将其释放到世界上,这个故事一直令人感到不安,弗兰肯斯坦也成为了科学过度伸张的代名词。

The cover illustration reimagines the monster first conjured in Mary Shelley's 1818 novel. Two centuries later, the story of how the fictional Dr. Frankenstein built a creature from scavenged body parts and unleashed it on the world has lost none of its power to unsettle, and Frankenstein has become a byword for scientific overreach.


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2018-01-19

封面图展示的是通过艺术手法渲染的一种长链自组装DNA平台,该平台上承载着多个转动臂。在平板上定义的插接站(黄色)之间,转动臂的运动能够通过外部应用电场精确引导。这种系统能够构成计算机控制的纳米机器人组装线的基础。在这种装置中,转动臂可以配合纳米级结构的合成。

Artistic rendering of a long chain of self-assembled DNA platforms bearing multiple rotor arms. The motion of the arms between docking stations (yellow) defined on the plates can be precisely directed by externally applied electric fields. Such systems could form the basis for computer-controlled nanorobotic assembly lines in which the arms cooperate in the synthesis of nanoscale structures.


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2018-01-26

封面图展示的是一只印度花豹正经过印度孟买的一条小巷。在经过人类改造的地区,哺乳动物的移动距离平均是它们在野外活动距离的二分之一到三分之一。对物种来说,减少的活动距离可能会对其生存能力及生态系统机能产生深远的影响。

A leopard (Panthera pardus fusca) walking through an alley in Mumbai, India. In human-modified landscapes, mammals move distances that are, on average, one-half to one-third the length of their movements in the wild. Reduced travel distances may have far-reaching consequences for species survival and ecosystem functioning.

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