邮发代码:82-418   刊号:ISSN1671-4350   定价:12.00

[点击科学]2019年5月点击科学

陶 陶 编译

2019-05/总第278期

阅读数4

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2019-03-29

T细胞(指能够破坏肿瘤的特殊免疫细胞)在发育过程中可能会失去功能,封面图上描绘的沿着倾斜轨道滚动的小球就代表T细胞。高水平的钾(图中橙色部分)使T细胞保持一种“茎状”状态,可以保持它们持续、分裂及对抗肿瘤的能力。具有干细胞性质的肿瘤特异性T细胞的存在有助于诠释癌症免疫疗法的实效性,以及指导改良疗法的设计。

T cells (specialized immune cells that can destroy tumors) may lose functionality during development, depicted here as balls rolling down sloped tracks. High levels of potassium (orange) preserve T cells in a "stem-like" state that maintains their ability to persist, divide, and fight tumors. The presence of tumor-specific T cells with stem cell?like properties helps to explain the effectiveness of cancer immunotherapies and guides the design of improved treatments.

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2019-04-05

封面图展示的是玉米植株的雄花。在减数分裂周期的起始阶段,玉米细胞将经历一系列复杂的步骤。通过单细胞RNA测序分析发育中的雄性生殖细胞,揭示出了独特的基因表达模式,并且阐明了减数分裂的进程。

Male flowers of the maize plant (Zea mays L. ssp. mays). Maize cells undergo a complex series of steps during the introductory stages of meiosis. Single-cell RNA sequencing analysis of developing male germinal cells reveals distinctive patterns of gene expression and sheds light on meiotic progress.

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2019-04-12

一项针对同卵双胞胎的研究发现,当双胞胎的其中一个在国际空间站生活了1年后,其分子、生理和认知都发生了特殊的变化。封面图以火箭和国际空间站为背景,描绘了这对双胞胎及他们各自在地球和太空的住所。

A study of identical twins identifies molecular, physiological, and cognitive changes specific to one twin who spent a year living aboard the International Space Station. The cover depicts the twins and their respective Earth-bound and space residencies, with a rocket and the International Space Station in the background.

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2019-04-19

封面图展示的是从隼鸟2号宇宙飞船上观察到的近地碳质小行星162173“龙宫”。这张超高分辨率的图像是由7张不同曝光的照片组合而成的。视图已经被旋转了;小行星的南方处于顶部。隼鸟2号对“龙宫”的形状、密度、表面特征及组成成分进行的测量表明,它很可能是由1颗更大的小行星撞击后喷射出的碎石再次堆积而成。

The near-Earth carbonaceous asteroid 162173 Ryugu, seen from the Hayabusa2 spacecraft. This super-resolution image was produced by combining seven separate exposures. The view has been rotated; south is at the top. Hayabusa2 measurements of Ryugu's shape, density, surface features, and composition indicate that it probably formed from reaccumulating rubble ejected from a larger asteroid as the result of an impact.

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