2022-04-29

封面图展示的是各种宠物狗的肖像，它们表现出了纯种和混种狗的各种身体特征。此外，不同的品种通常被认为具有不同的行为和个性。然而，根据参与“达尔文方舟”项目的数千只狗的数据表明，这种情况只是极少数，而研究狗的完全多样性才是理解基因、血统和行为等复杂特征之间相互作用的最好方法。

Portraits of pet dogs exemplify the assortment of physical characteristics seen in purebred and mixed-breed dogs. Additionally, different breeds are often thought to have distinctive behaviors and personalities. However, data from thousands of dogs involved in the Darwin’s Ark project reveal that this is rarely true, and that studying the full diversity of dogs is the best way to understand interactions between genetics, ancestry, and complex traits such as behavior.

2022-05-06

封面图展示的这些珊瑚礁位于印度洋马约特海岸附近，正如它们一样，许多珊瑚礁正在遭受人类活动的威胁。现在，通过在海葵模型系统中进行的生化实验表明，防晒成分氧苯酮在珊瑚礁生物中会转化为有毒的光敏剂。

Coral reefs, such as this site off the coast of Mayotte in the Indian Ocean, are under threat from many human activities. Biochemical experiments in a sea anemone model system now show that the sunscreen component oxybenzone is converted into toxic photosensitizers in reef-dwelling organisms.

2022-05-13

封面图展示的是对跨组织细胞类型的一份测绘图，作为人类细胞图谱的一部分，这份测绘图就这一课题在3篇论文中对单细胞转录组进行了绘制，为了解细胞组成和基因表达变化对人类身体健康的影响，以及了解基因在疾病中的作用等问题奠定了基础。

A survey of cell types across tissues as part of the Human Cell Atlas, mapped with single-cell transcriptomics in three papers in this issue, lays the foundation for understanding how cellular composition and gene expression vary across the human body in health, and for understanding how genes act in disease.

2022-05-20

封面图上的扫描电子显微图像展示了微小的球石藻浮游生物细胞壁覆盖物，它作为精美的化石印痕在1.83亿年前的侏罗纪有机物表面被保存了下来。球石藻是一种极为微小的海洋浮游植物，其坚硬的钙质板被称为颗石（约5微米长），通常具有丰富的化石记录。图中的这些球石藻已经从这些在全球变暖期间沉积下来的古老岩石中溶解，只留下了它们的“幽灵”印记。

Scanning electron micrograph of minuscule coccolithophorid plankton cell wall coverings preserved as exquisite fossil impressions on the surface of 183-million-year-old Jurassic organic matter. Coccolithophores are a type of microscopic marine phytoplankton, and their hard calcareous plates, called coccoliths (~5 micrometers long), are normally abundant in the fossil record. Here they have dissolved from these ancient rocks deposited during a global warming interval, leaving only their imprint “ghosts” behind.